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Alia A Sarafandi Selected Research

Isoleucine-tRNA Ligase

5/2005Efficacy, plasma pharmacokinetics, and safety of icofungipen, an inhibitor of Candida isoleucyl-tRNA synthetase, in treatment of experimental disseminated candidiasis in persistently neutropenic rabbits.
10/2004Efficacy of PLD-118, a novel inhibitor of candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and esophageal candidiasis caused by fluconazole-resistant C. albicans.

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Alia A Sarafandi Research Topics

Disease

2Body Weight (Weight, Body)
05/2005 - 10/2004
2Candidiasis (Moniliasis)
05/2005 - 10/2004
1Central Nervous System Infections (Central Nervous System Infection)
05/2005
1Infections
10/2004
1Invasive Pulmonary Aspergillosis
06/2003
1Lung Injury
06/2003
1Pulmonary Aspergillosis
06/2003

Drug/Important Bio-Agent (IBA)

2Isoleucine-tRNA LigaseIBA
05/2005 - 10/2004
22- amino- 4- methylenecyclopentane- 1- carboxylic acidIBA
05/2005 - 10/2004
2Amphotericin B (Amphotericin)FDA LinkGeneric
05/2005 - 10/2004
2Fluconazole (Zonal)FDA LinkGeneric
05/2005 - 10/2004
1Dihydrotachysterol (AT 10)IBA
05/2005
1Micafungin (FK463)FDA Link
06/2003
1TriazolesIBA
06/2003
1EchinocandinsIBA
06/2003
1ER 30346 (ravuconazole)IBA
06/2003

Therapy/Procedure

1Injections
10/2004
1Therapeutics
06/2003